A molecule’s ‘handedness’ can determine whether it’s an effective drug – 4 examples of pharmaceuticals where chirality matters
AI-rewritten: This is a summary of an article from The Conversation, rewritten by AI (Qwen, running locally) to make it easier to read. The facts come from the original article – read it for the full story.
The 2026 Nobel Prize in chemistry honors Henri Kagan and Kenso Soai for discovering how chemistry can favor one version of a molecule over its mirror image, known as chirality. Chiral objects, like spiral galaxies or human hands, have a reflection that cannot be perfectly aligned with the original. While most living things are built from only one specific form of molecules—a state called homochirality—early Earth likely had a balanced mix of both forms. Kagan found in the 1980s that a catalyst does not need to be entirely pure to produce a single-handed product, sometimes creating a purer result than itself. Soai discovered in the 1990s a molecule that copies itself and amplifies small imbalances into overwhelmingly one-handed mixtures, offering a possible explanation for how life chose its specific molecular handedness.